"A single psilocybin dose rapidly reverses chronic pain and depression in mice, study finds – "

https://www.naturalnews.com/2025-10-07-psilocybin-reverses-pain-depression-study.html 

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Scientists at the University of Pennsylvania found that psilocybin, the active ingredient in so-called magic mushrooms, provided lasting relief from chronic pain and depression-like symptoms in mice by calming overactive brain circuits. This research, published in the journal

Nature Neuroscience , offers a radical new pathway for treating the millions who suffer from the intertwined conditions of chronic pain and mental anguish..."